Advances in orofacial pathophysiology and regeneration (5025) | | Contact Person : | dr. Florian HERMANS |
| Language of instruction : English |
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| Degree programme | | Study hours | Credits | P4 SBU | P4 SP | 2nd Chance Exam1 | Tolerance2 | Final grade3 | |
 | 1st year Master of Biomedical Sciences - Environmental Health Sciences | Optional | 108 | 4,0 | 108 | 4,0 | Yes | Yes | Numerical |  |
| 1st year Master of Biomedical Sciences - Molecular Mechanisms in Health and Disease | Optional | 108 | 4,0 | 108 | 4,0 | Yes | Yes | Numerical | |
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| | | Learning outcomes |
- EC
| 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases. | - EC
| 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search. | - EC
| 3. A graduate of the Master of Biomedical Sciences can draw up a new research hypothesis based on his or her own findings or based on the findings of others, and work out a research proposal for this. | - EC
| 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards. | - EC
| 5. A graduate of the Master of Biomedical Sciences can independently process and statistically analyze research results, and formulate conclusions. | - EC
| 6. A graduate of the Master of Biomedical Sciences can report scientific findings in writing and orally to both experts and a wide audience in a structured way. | - EC
| 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others. | - EC
| 8. A graduate of the Master of Biomedical Sciences can actively participate in an international research environment. | - EC
| 11. A graduate of the Master of Biomedical Sciences can function in a multidisciplnary team and can fulfill a bridging function between the various actors in health care. The graduate knows the importance and needs of the various stakeholders within the life sciences. | - EC
| 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting. | - EC
| MHD 1. A graduate of the Master of Biomedical Sciences specialisation Molecular Mechanisms in Health and Disease has in depth insights in the etiology and the underlying molecular pathways of major disease areas (e.g. cardiovascular sciences, immunology and infection, neurosciences,...) |
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| | EC = learning outcomes DC = partial outcomes BC = evaluation criteria |
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At the end of the course the students will be familiar with the most important research directions and recent achievements in the field of orofacial biology and regeneration. In addition, the students should be able to understand and critically analyze recent scientific research papers in the field, and to adequately communicate such critical analysis in a public presentation.
Throughout the course, the students gain knowledge and insight in:
- Development and regeneration of teeth and salivary glands; their pathologies; relevant (3D) stem cell models;
- Recent omics technologies and their application in orofacial biomedical research (single cell transcriptomics, spatial transcriptomics, spatial proteomics, salivary proteomics)
- Biology and innervation of the jaw joint; and associated pathology
- The development and application of AI technology within (orofacial) radiology
- The physiology of orthodontic tooth movement, periodontal stem cells and periodontal regeneration
- Experimental design and methodology employed in (orofacial) biomedical research
- Developing experimental plans to tackle a scientific hypothesis
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Lecture ✔
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Tutorial group ✔
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Quarter 4 (4,00sp)
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| Oral evaluation during teaching period | 40 % |
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| Transfer of partial marks within the academic year | ✔ |
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| Other | Active participation in journal clubs |
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| Oral exam | 60 % |
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| Transfer of partial marks within the academic year | ✔ |
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| Other | Oral examination of the take-home assignment |
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| Evaluation conditions (participation and/or pass) | ✔ |
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| Conditions | 1) Attendance Guest Lectures is mandatory
2) Attendance Journal Clubs is mandatory
3) The evaluation consists of multiple parts. For all parts of the evaluation, at least a score of 8/20 must be obtained in order to pass for the course. |
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| Consequences | 1) Attendance at the guest lectures is obligatory unless there is a certified reason (illness, conference). The teaching team must be notified of all absences and students must provide a valid justification. In case absence is not justified, the student needs to write a critical evaluation on the missing lecture. In case absence is not justified and the report is not delivered, the student receives as final grade for the course a 'N unjustified absent' and must attend the guest lecture in the next academic year to receive their final grade. In this case, partial grades can be transferred to the next academic year.
2) Attendance at the journal club is obligatory unless there is a certified reason (illness, conference). The teaching team must be notified of all absences and students must provide a valid justification. In case of absence, the student needs to write a critical evaluation on the missing journal club (paper discussed). The score obtained on the critical evaluation will be taken into account for the final evaluation. In case the report is not delivered, the student receives as final grade for the course a 'N unjustified absent' and must attend the journal club in the next academic year to receive their final grade. In this case, partial grades can be transferred to the next academic year.
3) A student who achieves a score lower than 8/20 on one (or more) parts of the evaluation will receive "F fail" as final result. This final result is not tolerable.
A student who scores at least 8/20 for all parts of the evaluation receives as score a weighted average of the different grades. This final mark is tolerable. Eg. 8/20 + 16/20 = 12/20 (passed). |
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| Compulsory course material |
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Lecture slides and scientific articles on BB
COO's oral histology
Oral Histology, Ten Cate (digital available) |
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| Remarks |
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The course unit is only organized for a minimum of 8 students and a maximum of 20 students; the allocation is done by random draw with a computer program. The results of the draw are then announced on the first Monday of quarter 2. Students who were not assigned the course unit must make a new choice by December 15. |
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1 Education, Examination and Legal Position Regulations art.12.2, section 2. |
| 2 Education, Examination and Legal Position Regulations art.16.9, section 2. |
3 Education, Examination and Legal Position Regulations art.15.1, section 3.
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| Legend |
| SBU : course load | SP : ECTS | N : Dutch | E : English |
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