De elektronische studiegids voor het academiejaar 2025 - 2026 is onder voorbehoud.





Experimental Design in Molecular Mechanisms in Health and Disease (3950)

  
Coordinating lecturer :Prof. dr. Jerome HENDRIKS 
  
Co-lecturer :Prof. dr. Jeroen BOGIE 
  
Member of the teaching team :Mevrouw Aleksandra DYCZKO 
 De heer Alessio CARDILLI 
 dr. An VOETS 
 Prof. dr. Anitha ETHIRAJAN 
 dr. Annelies VANHEEL 
 dr. Beatriz FERNANDES CORTE-REAL 
 De heer Ben ROMBAUT 
 Prof. dr. Dries VANDAMME 
 Mevrouw Emily WILLEMS 
 Prof. dr. Esther WOLFS 
 Mevrouw Eva CORDERY 
 Prof. dr. Geert ROBAEYS 
 Prof. dr. Geert-Jan GRAULUS 
 Prof. dr. Judith FRAUSSEN 
 Prof. dr. Karen SMEETS 
 Prof. dr. Kris JANSSENS 
 Prof. dr. Leen SLAETS 
 dr. Lotte GEYS 
 Mevrouw Marithe CLAES 
 dr. Nele CLAES 
 Prof. dr. Nelly SAENEN 
 Prof. dr. Niels HELLINGS 
 dr. Paul HEEFFER 
 dr. Paulien BAETEN 
 De heer Peter BOGAERTS 
 dr. ir. Quirine SWENNEN 
 dr. Rik VERDONCK 
 dr. Sanne VERBERK 
 Prof. dr. Steven ABRAMS 
 dr. Tim VANGANSEWINKEL 
 Prof. dr. Werend BOESMANS 
 Prof. dr. Wim PINXTEN 


Language of instruction : English


Credits: 8,0
  
Period: quarter 1 (8sp)
  
2nd Chance Exam1: Yes
  
Final grade2: Numerical
 
Exam contract: not possible


 
Sequentiality
 
   Advising sequentiality bound on the level of programme components
 
 
  Following programme components are advised to also be included in your study programme up till now.
    Bachelor's thesis (3748) 9.0 stptn
    Multidisciplinary biomedical research (5483) 7.0 stptn
 

Content

General aims
In this teaching block, the student will learn how experiments are designed, how results are analysed and communicated, and how follow up research is designed.

Concrete aims
After completion of this teaching block, the student has insight into:

  • Hypothesis and problem statement
  • Study design
  • The design and interpretation of figures
  • Poster design and presentation
  • Applied statistics
  • Communication of research findings
  • Scientific fraud and integrity
  • Validation and verification of scientific findings
  • Scientific English

In the MHD master the students gain insight in the molecular disease mechanisms underlying diseases such as COPD, atherosclerosis and cancer and the impact of nutrition and aging hereon. Also, the students learn how research is designed in these disease domains.



Organisational and teaching methods
Organisational methods  
Collective feedback moment  
Lecture  
Self-study assignment  
Small group session  


Evaluation

Period 1    Credits 8,00

Evaluation method
Written evaluaton during teaching periode40 %
Transfer of partial marks within the academic year
Report
Oral evaluation during teaching period20 %
Transfer of partial marks within the academic year
Debat
Written exam40 %
Transfer of partial marks within the academic year
Open questions
Evaluation conditions (participation and/or pass)
Conditions Presence at the journal clubs and tutor sessions is obligatory. The evaluation consists of multiple parts. For all parts of the evaluation, at least a score of 8/20 must be obtained in order to pass for the course.
Consequences Students who are unjustified absent at the journal clubs or tutor sessions, receive as final grade for the course a N unjustified absent and have to attend the journal club in the next academic year to receive their final grade. The student needs to re-enroll in the course in the next academic year. In this case, partial grades can be transferred to the next academic year. A student who achieves a score lower than 8/20 on one (or more) parts of the evaluation will receive F fail as final result. This final result is not tolerable. A student who scores at least 8/20 for all parts of the evaluation receives as score a weighted average of the different grades. This final mark is tolerable. Eg. 8/20 + 16/20 = 12/20 (passed).

Second examination period

Evaluation second examination opportunity different from first examination opprt
No
 

Compulsory textbooks (bookshop)
 

Textbook 1:

Hofmann A, Scientific writing and communication, 5th edition, Oxford University Press

ISBN: 9780197613795

 

Compulsory course material
 

Handouts of presentations and additional course material posted on blackboard



Learning outcomes
Master of Biomedical Sciences
  •  EC 
  • 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases.

  •  EC 
  • 10. A graduate of the Master of Biomedical Sciences  knows the potential for valorization of biomedical research and can translate own research into translational research. 

  •  EC 
  • 11. A graduate of the Master of Biomedical Sciences can function in a multidisciplnary team and can fulfill a bridging function between the various actors in health care. The graduate knows the importance and needs of the various stakeholders within the life sciences.

  •  EC 
  • 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting.

  •  EC 
  • 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search.

  •  EC 
  • 3. A graduate of the Master of Biomedical Sciences can draw up a new research hypothesis based on his or her own findings or based on the findings of others, and work out a research proposal for this.

  •  EC 
  • 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards.

  •  EC 
  • 5. A graduate of the Master of Biomedical Sciences can independently process and statistically analyze research results, and formulate conclusions. 

  •  EC 
  • 6. A graduate of the Master of Biomedical Sciences  can report scientific findings in writing and orally to both experts and a wide audience in a structured way.

  •  EC 
  • 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others.   

  •  EC 
  • 9. A graduate of the Master of Biomedical Sciences can set up, conduct and report biomedical research in an ethical manner and with integrity, taking into account current regulations.  

  •  EC 
  • MHD 1. A graduate of the Master of Biomedical Sciences specialisation Molecular Mechanisms in Health and Disease has in depth insights in the etiology and the underlying molecular pathways of major disease areas (e.g. cardiovascular sciences, immunology and infection, neurosciences,...)

 

Master of Teaching in Health Sciences
  •  EC 
  • 5.1 The educational master is a domain expert HEALTH SCIENCES: the EM has an understanding of the construction and functioning of the human body in disease and health (at the molecular, cellular, organ and organism level).

  •  EC 
  • 5.4  The educational master is a domain expert HEALTH SCIENCES: the EM can independently and critically conduct literature research, formulate and operationalise a research question (-hypothesis), collect research data, process the obtained research results, interpret and report orally and in writing.

 

  EC = learning outcomes      DC = partial outcomes      BC = evaluation criteria  
Offered inTolerance3
1st year Master of Biomedical Sciences - Molecular Mechanisms in Health and Disease J
Master of Teaching in Health Sciences keuzetraject BMW/GEN met vakdidactiek biologie J
Master of Teaching in Health Sciences keuzetraject BMW/GEN met vakdidactiek chemie J



1   Education, Examination and Legal Position Regulations art.12.2, section 2.
2   Education, Examination and Legal Position Regulations art.15.1, section 3.
3   Education, Examination and Legal Position Regulations art.16.9, section 2.