De elektronische studiegids voor het academiejaar 2025 - 2026 is onder voorbehoud.





Biomarker detection and prevention (3963)
  
Coordinating lecturer :Prof. dr. Karen SMEETS 
  
Co-lecturer :Prof. dr. Patrick DE BOEVER 
  
Member of the teaching team :Mevrouw Jolien VAN HAARLEM 
 Prof. dr. Nelly SAENEN 
 dr. Rik VERDONCK 
 Mevrouw Yinthe DOCKX 

Language of instruction : English
Credits: 4,0
  
Period: quarter 2 (4sp)
  
2nd Chance Exam1: Yes
  
Final grade2: Numerical
 
Exam contract: not possible
 
Sequentiality
 
   Mandatory sequentiality bound on the level of programme components
 
 
  Following programme components must have been included in your study programme in a previous education period
    System toxicology (3962) 8.0 stptn
 

Content

Part 1: Types of biomarkers and toxicity assays

  • Biomarkers of injury/ disease/ Biomarkers of environmental exposure
  • Carcinogenicity assays/ skin irritation assays/ stem cell - derived systems
  • Assay development and validation

Part 2: Design, study and technology for biomarker discovery

  • Transcriptomic, metabolomic and proteomic profiling for biomarker discovery, study and technology
  • In silico methods
  • Adverse Outcome Pathways

Part 3: Prevention and regulatory concepts

  • Biomarkers, surveillance and prevention
  • Individual susceptibility
  • Regulatory concepts


Organisational and teaching methods
Organisational methods  
Lecture ✔  
Response lecture ✔  
Self-study assignment ✔  
Teaching methods  
Case study ✔  


Evaluation

Period 2    Credits 4,00

Evaluation method
Written evaluaton during teaching periode15 %
Transfer of partial marks within the academic year✔
Written exam85 %
Closed-book ✔
Case study✔
Open questions✔

Second examination period

Evaluation second examination opportunity different from first examination opprt
No
 

Compulsory course material
 

Course material is available via blackboard.


Learning outcomes
Master of Biomedical Sciences
  •  EC 

    • 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases.

  •  EC 

    • 10. A graduate of the Master of Biomedical Sciences  knows the potential for valorization of biomedical research and can translate own research into translational research. 

  •  EC 

    • 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting.

  •  EC 

    • 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search.

  •  EC 

    • 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards.

  •  EC 

    • 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others.   

  •  EC 

    • EHS 1. A graduate of the Master of Biomedical Sciences specialisation Environmental Health Sciences has insights in the effects of external factors on health at the molecular, cellular and organ level.

  •  EC 

    • EHS 3. A graduate of the Master of Biomedical Sciences specialisation Environmental Health Sciences possesses basic knowledge and skills regarding biomarkers of exposure and effect, risk analysis and biostatistical processing of results from experimental and population based research. 

 
Master of Teaching in Sciences and Technology
  •  EC 

    • 5.4. The master of education is a domain expert SCIENCES: the EM has advanced knowledge and understanding of the domain disciplines relevant to the specific subject doctrine(s).

 
  EC = learning outcomes      DC = partial outcomes      BC = evaluation criteria  
Offered inTolerance3
1st year Master of Biomedical Sciences - Environmental Health Sciences J
Master of Teaching in Sciences and Technology - choice for subject didactics Biology J



1   Education, Examination and Legal Position Regulations art.12.2, section 2.
2   Education, Examination and Legal Position Regulations art.15.1, section 3.
3   Education, Examination and Legal Position Regulations art.16.9, section 2.