De elektronische studiegids voor het academiejaar 2025 - 2026 is onder voorbehoud.





Biosensors (3967)

  
Coordinating lecturer :Prof. dr. Anitha ETHIRAJAN 
  
Member of the teaching team :dr. Bernhard SIEGMUND 
 De heer Faran TAHIR 
 Mevrouw Nora COLSON 
 dr. ir. Rani MARY JOY 
 De heer Thomas LEENDERTSE 


Language of instruction : English


Credits: 5,0
  
Period: quarter 2 (5sp)
  
2nd Chance Exam1: Yes
  
Final grade2: Numerical
 
Exam contract: not possible


 
Sequentiality
 
   Mandatory sequentiality bound on the level of programme components
 
 
  Following programme components must have been included in your study programme in a previous education period
    Liquids, solids, and biological matter: structure and transport mechanisms (2131) 4.0 stptn
 
   Advising sequentiality bound on the level of programme components
 
 
  Following programme components are advised to also be included in your study programme up till now.
    Chemistry of surfaces (3968) 5.0 stptn
 

Content

Course Content:

- Introduction to Biosensors: Important terms, definitions, components of a biosensor, Transducer and principles of operation, Biosensors-needs and demand

- Recognition elements, immobilization strategies, assay formats, sensor characteristics and requirements

- Piezoelectric transducers (Microgravimetric sensors, microbalances)

- Optical sensors (surface plasmon resonance, techniques based on total internal reflection)

- Electrochemical sensors (Potentiometric, amperometric, impedimetric, ion-selective, FET)

- Bioelectronic devices (e.g. organic bioelectronics in vitro and in vivo)

- Recent advances in the field

Learning goals:

The student can explain the components of a biosensor and different transducer principles

The student has insight on the requirements of a biosensor

The students can explain different technological layouts and working principles of bioelectronic devices

The student has insight on various state-of-the-art techniques playing an important role in the detection of biomolecules, metabolites, and organic/inorganic contaminants.

The student can select a suitable technique for the diagnosis of metabolic disorders, the early detection of diseases such as cancers as well as in environmental monitoring and food safety.



Organisational and teaching methods
Organisational methods  
Lecture  
Practical  
Small group session  
Teaching methods  
Discussion/debate  
Group work  
Presentation  
Report  


Evaluation

Period 2    Credits 5,00

Evaluation method
Written evaluaton during teaching periode15 %
Transfer of partial marks within the academic year
Report
Oral evaluation during teaching period15 %
Transfer of partial marks within the academic year
Presentation
Oral exam70 %
Evaluation conditions (participation and/or pass)
Conditions Presence at the practical sessions, Journal club discussions and presentation (assignment) is obligatory The practical reports, the journal club and the assignment scores are part of the final result. Practical reports must always be submitted.
Consequences Students who are unauthorized absent at one or more practica, receive as final grade for the course a N - unauthorized absence' and have to attend the practicum in the next academic year and have to meet the requirements (e.g. a signed report) to receive their final grade. The student needs to re-enroll in the course in the next academic year. In this case, partial grades can be transferred to the next academic year. Those who do not submit practical reports will receive an N - unauthorized absence as the end result.
Additional information

Written valuation during teaching period (15%): Reports of practicals (15%)

Oral evaluation during teaching period (15%): Presentation (10%) and journal club & discussion (5%)

Oral exam (70%): closed book


Second examination period

Evaluation second examination opportunity different from first examination opprt
No
 

Compulsory course material
 

All lecture and excersise materials will be available through Blackboard or distributed during the lecture



Learning outcomes
Master of Biomedical Sciences
  •  EC 
  • 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases.

  •  EC 
  • 11. A graduate of the Master of Biomedical Sciences can function in a multidisciplnary team and can fulfill a bridging function between the various actors in health care. The graduate knows the importance and needs of the various stakeholders within the life sciences.

  •  EC 
  • 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting.

  •  EC 
  • 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search.

  •  EC 
  • 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards.

  •  EC 
  • 6. A graduate of the Master of Biomedical Sciences  can report scientific findings in writing and orally to both experts and a wide audience in a structured way.

  •  EC 
  • BEN 1. A graduate of the Master of Biomedical Sciences specialisation Bioelectronics and Nanotechnology is able to describe and apply different (bio-) electronic sensor modalities to detect biochemical and bioelectrical effects at different levels of a healthy or diseased organisms.

  •  EC 
  • BEN 2. A graduate of the Master of Biomedical Sciences specialisation Bioelectronics and Nanotechnology is able to give a broad overview of the manipulation as well as use of key materials in bio-electronics and biological material in biosensors for a better diagnosis and therapy of human diseases.

  •  EC 
  • BEN 3. A graduate of the Master of Biomedical Sciences specialisation Bioelectronics and Nanotechnology has a comprehensive understanding of, and the ability to determine the (bio)chemical and physical characteristics of various materials and their applications in life sciences.

  •  EC 
  • BEN 4. A graduate of the Master of Biomedical Sciences specialisation Bioelectronics and Nanotechnology has technical skills in material development, several nano- and micro fabrication methods, and a broad variety of physical, chemical and biological characterization techniques that enable interdisciplinary approaches for advanced diagnosis and therapy.

 

Master of Teaching in Sciences and Technology
  •  EC 
  • 5.4. The master of education is a domain expert SCIENCES: the EM has advanced knowledge and understanding of the domain disciplines relevant to the specific subject doctrine(s).

 

  EC = learning outcomes      DC = partial outcomes      BC = evaluation criteria  
Offered inTolerance3
1st year Master of Biomedical Sciences - Bioelectronics and Nanotechnology J
Master of Teaching in Sciences and Technology - choice for subject didactics Physics J



1   Education, Examination and Legal Position Regulations art.12.2, section 2.
2   Education, Examination and Legal Position Regulations art.15.1, section 3.
3   Education, Examination and Legal Position Regulations art.16.9, section 2.