De elektronische studiegids voor het academiejaar 2026 - 2027 is onder voorbehoud.





System toxicology (3962)

Coordinating lecturer:Prof. dr. Michelle PLUSQUIN 
Co-lecturer:Prof. dr. Tim NAWROT 
Member of the teaching team:dr. Brigitte REIMANN 
 dr. Hanne CROONS 
 dr. Kenneth VANBRABANT 
 Prof. dr. Nelly SAENEN 
 Prof. dr. Patrick DE BOEVER 
 dr. Rossella ALFANO 
 dr. Sofie THIJS 


Credits: 8,0
Study load hours: 216
Period: quarter 1 (8sp)

Language of instruction: English
Exam contract: not possible

2nd Chance Exam1: Yes
Final grade2: Numerical
Tolerance3: See included in these programmes

Sequentiality
No sequentiality


Content

The students will acquire a systems biological perspective to explore the most recent findings linking environmental exposures and life style choices to human disease and health.

The students will acquire the following learning goals:

The student has an understanding of the human metabolic processes that are induced by external elements as well as the combined actions of cell cycle, signal transduction and cytotoxicity.

The student has insight in technologies in the domain of omics with pathway and network analyses included.

The student has insight in the different molecular levels involved in the effect external exposures on the cell.

The student has an understanding of the principles of toxicology applied to several organ systems, including disturbances in anatomy and physiology of the immune, neurlogical, cardiovascular, endocrine and respiratory system.

The student has an understanding of the molecular ageing process focussing on telomere biology and the epigenetic clock.

The student has understanding of the developmental origin of disease hypothesis.



Compulsory textbooks (bookshop)
  ,
 

Mandatory software
 


Organisational and teaching methods
Organisational methods  
Lecture  
Practical  
Project  
Self-study assignment  
Teaching methods  
Case study  
Discussion/debate  
Paper  


Evaluation

Quarter 1 (8,00sp)

Evaluation method
Oral evaluation during teaching period20 %
Presentation
Practical evaluation during teaching period5 %
Written exam55 %
Multiple-choice questions
Open questions
Oral exam20 %
Open questions
Additional information

Oral evaluation method during teaching period: presentation, podcast


Second examination period

Evaluation second examination opportunity different from first examination opprt
No


Learning outcomes
  EC = learning outcomes      DC = partial outcomes      BC = evaluation criteria  
Master of Biomedical Sciences
  •  EC 
  • 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases.

  •  EC 
  • 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting.

  •  EC 
  • 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search.

  •  EC 
  • 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards.

  •  EC 
  • 6. A graduate of the Master of Biomedical Sciences  can report scientific findings in writing and orally to both experts and a wide audience in a structured way.

  •  EC 
  • 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others.   

 

Included in these programmesTolerance3
1st year Master of Biomedical Sciences - Environmental Health Sciences Y
Master of Teaching in Sciences and Technology - choice for subject didactics Biology Y



1   Education, Examination and Legal Position Regulations art.12.2, section 2.
2   Education, Examination and Legal Position Regulations art.15.1, section 3.
3   Education, Examination and Legal Position Regulations art.16.9, section 2.