De elektronische studiegids voor het academiejaar 2025 - 2026 is onder voorbehoud.





Drug delivery, pharmacology & toxicology (3959)

  
Coordinating lecturer :Prof. dr. Nelly SAENEN 
  
Co-lecturer :Prof. dr. Karen SMEETS 
  
Member of the teaching team :dr. Karolien BIJNENS 
 Prof. dr. Kurt VAN DER SPEETEN 
 Mevrouw Margo WITTERS 
 dr. Rik VERDONCK 


Language of instruction : English


Credits: 3,0
  
Period: quarter 4 (3sp)
  
2nd Chance Exam1: Yes
  
Final grade2: Numerical
 
Exam contract: not possible


 
Sequentiality
 
   No sequentiality

Content

Course content:

  • Introduction to “Drug delivery, Pharmacology, and Toxicology”
  • PART 1: From basic to controlled drug delivery
    • Pharmacokinetics of drugs
    • Drug delivery systems: from basic to controlled
    • Toxicity tests
  • PART 2: Advanced drug delivery
    • Targeting strategies and its clinical applications
    • Barriers to overcome
    • Toxicity of ‘new emerging compounds'
  • PART 3: Preclinical Validation
    • Preclinical validation using case studies

Learning goals:

  • The student has insight in the pharmacokinetics of drugs
  • The student can explain different drug delivery systems typically used for drug delivery, including controlled release
  • The student can explain active and passive targeting drug delivery and has insight in its potential applications
  • The student has insight in (particle) toxicity of drug delivery systems and how to take this into account in validation studies
  • The student has insight in the trajectory of validation studies and can relate the interplay between research and clinical phases (MHD/KBW/Elective course)


Organisational and teaching methods
Organisational methods  
Lecture  
Small group session  
Tutorial group  
Teaching methods  
Discussion/debate  
Group work  
Presentation  
Report  


Evaluation

Period 4    Credits 3,00

Evaluation method
Written evaluaton during teaching periode15 %
Transfer of partial marks within the academic year
Case study
Oral evaluation during teaching period10 %
Transfer of partial marks within the academic year
Presentation
Written exam75 %
Open questions
Evaluation conditions (participation and/or pass)
Conditions Presence at the Journal clubs and assignment(s) is obligatory. The evaluations consist of multiple parts. For all parts of the evaluation, at least a score of 8/20 must be obtained in order to pass the course.
Consequences Students who are unjustifiably absent from the journal club or assignment presentation receive an N-unjustified absence as a final grade for the course and have to attend the missed journal club/assignment in the next academic year to receive their final grade. The student needs to re-enrol in the course in the next academic year. In this case, partial grades can be transferred to the next academic year. A student who achieves a score lower than 8/20 on one (or more) parts of the evaluation will receive 'F - fail' as the final result. This final result is not tolerable. A student who scores at least 8/20 for all parts of the evaluation receives a score that is the weighted average of the different points. This final mark is tolerable. E.g., 8/20 + 16/20 = 12/20 (passed).
Additional information

Oral evaluation during the teaching period includes moderator skills during the journal club.


Second examination period

Evaluation second examination opportunity different from first examination opprt
No
 

Compulsory course material
 

All lecture materials will be available on blackboard.



Learning outcomes
Master of Biomedical Sciences
  •  EC 
  • 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases.

  •  EC 
  • 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting.

  •  EC 
  • 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search.

  •  EC 
  • 3. A graduate of the Master of Biomedical Sciences can draw up a new research hypothesis based on his or her own findings or based on the findings of others, and work out a research proposal for this.

  •  EC 
  • 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards.

  •  EC 
  • 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others.   

 

  EC = learning outcomes      DC = partial outcomes      BC = evaluation criteria  
Offered inTolerance3
1st year Master of Biomedical Sciences - Environmental Health Sciences J



1   Education, Examination and Legal Position Regulations art.12.2, section 2.
2   Education, Examination and Legal Position Regulations art.15.1, section 3.
3   Education, Examination and Legal Position Regulations art.16.9, section 2.