| Language of instruction : English |
| Exam contract: not possible |
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Sequentiality
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No sequentiality
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| Degree programme | | Study hours | Credits | P2 SBU | P2 SP | 2nd Chance Exam1 | Tolerance2 | Final grade3 | |
 | 1st year Master of Biomedical Sciences - Environmental Health Sciences | Optional | 162 | 6,0 | 162 | 6,0 | Yes | Yes | Numerical |  |
| 1st year Master of Biomedical Sciences - Molecular Mechanisms in Health and Disease | Optional | 162 | 6,0 | 162 | 6,0 | Yes | Yes | Numerical | |
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| | | Learning outcomes |
- EC
| 1. A graduate of the Master of Biomedical Sciences has a thorough knowledge of the molecular and cellular processes of the healthy and diseased organism and has insight in different methods for prevention, diagnosis and therapy of diseases. | - EC
| 2. A graduate of the Master of Biomedical Sciences can independently and critically perform a literature search. | - EC
| 3. A graduate of the Master of Biomedical Sciences can draw up a new research hypothesis based on his or her own findings or based on the findings of others, and work out a research proposal for this. | - EC
| 4. A graduate of the Master of Biomedical Sciences has knowledge of state-of-the-art techniques within biomedical research and is able to apply these techniques, taking into account the applicable quality standards. | - EC
| 6. A graduate of the Master of Biomedical Sciences can report scientific findings in writing and orally to both experts and a wide audience in a structured way. | - EC
| 7. A graduate of the Master of Biomedical Sciences takes a critical attitude towards one's own research and that of others. | - EC
| 8. A graduate of the Master of Biomedical Sciences can actively participate in an international research environment. | - EC
| 9. A graduate of the Master of Biomedical Sciences can set up, conduct and report biomedical research in an ethical manner and with integrity, taking into account current regulations. | - EC
| 10. A graduate of the Master of Biomedical Sciences knows the potential for valorization of biomedical research and can translate own research into translational research. | - EC
| 11. A graduate of the Master of Biomedical Sciences can function in a multidisciplnary team and can fulfill a bridging function between the various actors in health care. The graduate knows the importance and needs of the various stakeholders within the life sciences. | - EC
| 12. A graduate of the Master of Biomedical Sciences has an attitude for lifelong learning and for constantly adjusting one's own professional thinking and acting. |
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| | EC = learning outcomes DC = partial outcomes BC = evaluation criteria |
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This course aims at the careful and responsible use of animals in biomedical research, in accordance with the Belgian and European legislation.
According to the legal requirements (Annex 8 of the Royal Decree of 6 April 2010 on the protection of animals), the course of laboratory animal science in Belgium to obain the certificate FELASA C* (experiment leader) takes 80 hours of education. The experiment leader is responsible for research projects involving laboratory animals. In Belgium, this certificate may only be granted to holders of a university degree, who also followed the accredited training required by the FPS ** .
The laboratory animal science course is a compulsory course in the first year of the master MHD and EHS. The student has the choice between either the course 3953, ie the course approved by the government, or a theoretical variant without practice, ie "Theoretical basis of Laboratory Animal Science" (3954).
The program covers the following topics, in accordance with the legal requirements :
- History of animal sciences
- Ethics in animal sciences
- Legislation
- Zootechnology, Anesthesia, euthanasia, human endpoints, welfare, safety, GLP and health monitoring
- Statistics of animal research
- Genetic standardization and transgenesis
- Alternative models: Zebrafish , Drosophila
- Animal models of disease: cognition, neuroimmunology, spinal cord injury, cardiology
- Animal facility
- Surgical techniques
- Practical techniques (animal handling and fixation, injection, sex dertermination, anesthesia)
- Ethical matrix
* FELASA: Federation of European Laboratory Animal Science Associations
** FPS: Federal Public Service Health, Food Chain Safety and Environment
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Demonstration ✔
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Discussion/debate ✔
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Group work ✔
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Presentation ✔
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Report ✔
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Period 2 Credits 6,00
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| Written evaluaton during teaching periode | 25 % |
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| Transfer of partial marks within the academic year | ✔ |
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| Other | The group work also includes peer evaluation |
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| Oral evaluation during teaching period | 15 % |
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| Transfer of partial marks within the academic year | ✔ |
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| Evaluation conditions (participation and/or pass) | ✔ |
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| Conditions | The evaluation consists of multiple parts. For all parts of the evaluation, at least a score of 8/20 must be obtained in order to pass for the course.
Each student has to contribute sufficiently to the group assignment. |
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| Consequences | A student who achieves a score lower than 8/20 on one (or more) parts of the evaluation will receive a ‘F fail’ 'fail' as final result. This final result is not tolerable.
A student who achieves an 8/20 or 9/20 on one (or more) parts of the evaluation will receive 9/20 as the final result, regardless of the weighted average of the scores. This final mark is tolerable.
Eg. 8/20 + 16/20 = 9/20 (tolerable)
A student who possibly has participated significantly less in the group assignment than the other group members, will follow the free-riding behavior process as explained on Blackboard. During this process, the student will receive a temporary score “X” (no exam grade available). If free-riding behavior is identified, the student will receive “F” (fail) as final score for the course, and will receive an alternative assignment during the second-chance exam period. The results of the other evaluation parts can be retained for the second-chance exam if the student has passed or had received a tolerable mark. |
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| Additional information | When working in team, sufficient input from each student is expected. Peer evaluation is done by the Buddycheck program on Blackboard. For each student, the score of the group work will be multiplied by the factor that is calculated by this program. The method of calculation and the way this process works, is further explained on Blackboard. If there is a potentially significant smaller contribution, the process regarding free-riding behavior will be started. |
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| Prerequisites |
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This course is based on knowledge in morphology, (neuro)physiology, gene technology, immunology, microbiology, pathology, toxicology and statistics, and basic practical laboratory skills.
knowledge:
Basic knowledge on de function of the body with respect to metabolism, pain, stress, and behaviour
Basic knowledge on statistics Scentific method Techniques for scientific research
Practical skills:
Dilutions
Calculation of concentration
Use of syringe/injection |
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| Compulsory course material |
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Handouts of lectures and additional information posted on blackboard |
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| Recommended reading |
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principles of laboratory animal sciences,Van Zutphen et al,revised edition 2001,Elsevier,9780444506122,available in Dutch and English |
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1 examination regulations art.1.3, section 4. |
| 2 examination regulations art.4.7, section 2. |
3 examination regulations art.2.2, section 3.
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| Legend |
| SBU : course load | SP : ECTS | N : Dutch | E : English |
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